Objective:To investigate the diagnostic value of high-frequency ultrasound in nipple adenoma(NA).Methods:The preoperative ultrasonographic findings of 55 patients pathologically confirmed NA in the First Affiliated Hospital of Zhengzhou University from January 2012 to December 2022 were retrospectively analyzed.The location,internal echo,mor-phology,boundary,blood flow signal,the neighborhood relationship between the lesion and the surrounding area and whether there were any accompanying breast lesions.Results:The ultrasonic manifestations of NA were diversified.The ultrasound im-ages were divided into four types:①nodular type,18 cases(32.7%),nodular mass in the nipple or at the root of the nipple,oval shaped,well-demarcated,17 cases were solid hypoechoic and the other was cystic solid one.The diameter of the nodule was 3.7～22 mm,and the color Doppler flow showed not rich blood flow;②swollen nipple type,16 cases(29.1%),swollen nip-ple,echo reduction and abundant blood flow signals;③dilation of the central duct type,7 cases(12.7%)with a width of ap-proximately 2.0～4.5 mm with good internal sound transmission;④no special phenotype,14 cases(25.5%)showed no special ul-trasonic findings.There were 36 cases in the simple NA group,14 cases in NA combined with benign lesions group and 5 cases in the NA combined with malignant lesions group.Over 50-year-old(60%)in the NA combined with malignant lesions group was significantly higher than that of the simple NA group(16.7%),and the difference was statistically significant(P=0.028).Conclusion:NA can occur alone or coexist with benign or malignant lesions.The sonographic characteristics of NA were displayed via ultrasound,providing imaging support for clinical diagnosis and treatment.
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