Objective:Exploring the feasibility of using dynamic load CT myocardial perfusion imaging(CT-MPI)combined with cardiac magnetic resonance imaging(CMR)to evaluate coronary microcirculation disorders(CMD)in hypertensive patients.Method:Sixty-four hypertensive patients admitted to our hospital from January 2022 to June 2023 due to suspected coronary heart disease were included,using CT-MPI,CMR and IMR examinations,divide into study group and control group according to the CMD standard of IMR＞25,compare the differences in CT-MPI and CMR examination parameters between two groups of patients,using Pearson correlation analysis to examine the correlation between CT-MPI and CMR parameters and IMR values,using regression models to analyze the consistency between CT-MPI combined with CMR to check parameter predictions and IMR detection results,the value of using ROC curve analysis to evaluate the occurrence of CMD in hypertensive patients us-ing CT-MPI,CMR and regression model-based joint assessment.Result:The MBF,MBV,LVEF,Slopmax and SLpeak of the study group were lower than those of the control group,while TTP,LVMI,LVEDV,LVESV and tpeak were higher than those of the control group,with statistical significance(P＜0.05).CT-MPI and CMR indicators were significantly correlated with IMR val-ues,with statistical significance(P＜0.05).The predicted values of the logistic regression model have good consistency with the IMR detection results,the false positive rate is 3.45%.The ROC curve analysis results show that the sensitivity of six indi-cators,MBF,MBV,LVMI,LVEF,LVEDV and SLpeak is less than 0.8,indicating a high rate of missed diagnosis.The combi-nation of CT-MPI and CMR based on logistic regression predicts a sensitivity of 1.00 and a specificity of 0.966,indicating high evaluation value.The CT-MPI myocardial 17 segment MBF results showed that the MBF values in the load state 4,5,7,10 and 15 segments of CMD patients were lower than those in the rest state,and these segments may be the main regions of CMD occurrence.Conclusion:CT-MPI and CMR can reveal the existence of CMD to a certain extent.The combination of CT-MPI and CMR based on regression model prediction and IMR detection results has good consistency,and has high value in evaluating coronary microcirculation disorders in hypertensive patients.
维普
万方数据