Objective:To compare the detection rates of prostate cancer(PCa)between the transperineal(TP)systematic biopsy and TP multimodal imaging targeted biopsy.Methods:A total of 120 clinically suspected PCa patients were randomly divided into a systematic group(n=60)and a targeted group(n=60).TP biopsy was performed separately,with 12 cores per case in the systematic group and 10～13 cores per case in the targeted group.Targeted group patients underwent multimodal ultra-sound or/and multi-parameter MRI(mp-MIR)examination before biopsy,and an 8+X(systematic+suspicious lesion)biopsy strat-egy was implemented.The detection rates of PCa between two groups were compared.Results:There were no statistically sig-nificant differences in the detection rates of PCa and non clinically significant PCa between the two groups(P>0.05),while the detection rate of clinically significant prostate cancer(csPCa)in the targeted group was higher than that in the system group(χ2=10.497,P=0.038).The positive rate of single core for prostate cancer in the targeted group was higher than that in the systematic group(31.09%vs.23.47%;χ2=10.497,P=0.001).There was no statistically significant difference in Gleason score distribution between the two groups of PCa patients(χ2=8.213,P=0.084).Both groups of patients had no serious postoperative complications.Conclusions:Compared with systematic TP biospy,targeted TP biopsy has a higher detection rate of csPCa,and multimodal imaging has clinical application value in improving the detection of csPCa.
维普
万方数据