Therapeutic effect evaluation of microwave ablation for uterine benign lesions under ultrasound-guided local infiltration anesthesia and analysis of associated influencing factors
Therapeutic effect evaluation of microwave ablation for uterine benign lesions under ultrasound-guided local infiltration anesthesia and analysis of associated influencing factors
Objective:To investigate the therapeutic efficacy of microwave ablation for uterine fibroids and adenomyosis under ultrasound-guided local infiltration anesthesia and explore the associated influencing factors.Methods:According to the inclusion and exclusion criteria,63 patients who received microwave ablation for symptomatic uterine benign lesions under ultrasound-guided local infiltration anesthesia in Shengjing Hospital of China Medical University were retrospectively collected from January 2022 to December 2023.The therapeutic efficacy of microwave ablation was assessed at 1-,3-,6-month follow-ups.Correlation analysis was performed to explore the relationship between the basic clinical information of the patients and the therapeutic efficacy.Results:A total of 17 patients completed the 6-month follow-up.Both uterine volume and non-perfused zone volume of lesion were significantly decreased compared with the last examination(P<0.05),showing a gradual descending,with a final uterine volume reduction rate of 44.3%(41.6%~58.2%)and a non-perfused zone volume of lesion reduction rate of 76.6%(65.3%~84.0%)The therapeutic efficacy in 11 patients(64.7%)was very significant,and 6 patients(35.3%)was significant with no serious postoperative complications.The uterine volume reduction rate correlated with BMI and uterine volume at 1-,3-,and 6-month follow-ups,and non-perfused zone volume of lesion reduction rate correlated with total ablation energy per unit volume and lesion volume at 1-,3-month follow-ups.Conclusion:Microwave ablation for uterine fibroids and adenomyosis under ultrasound-guided local infiltration anesthesia has good safety and efficacy.