The most prevalent and significant malignant tumors of the hematopoietic system include leukemia,lymphoma and myeloma.It has been demonstrated in recent years that the patient 's body composition has a significant impaction on the prognosis of these tumors.Thus,the evaluation of body composition is crucial in the patient management.Several imaging technologies,including quantitative CT and MRI,could not only provide precise anatomical details,but also directly quantify information of body composition with the advantages of repeatability and objectivity,including muscle,adipose,and bone min-eral density.It has been demonstrated that the quantitative parameters of muscle,adipose are of positive value in predicting treatment response and survival prognosis for lymphoma,myeloma and leukemia.The development of body composition analysis using CT and MRI for assessing the prognosis and survival of the three major hematological malignancies mentioned above is reviewed in this paper.