Objective:To explore the predictive value of multi-slice spiral CT (MSCT) enhancement scan in recurrence of hepatocellular carcinoma (HCC) after interventional therapy. Methods:The clinical data were collected from 102 patients with HCC who underwent interventional therapy in the hospital between June 2019 and March 2023. All patients underwent MSCT enhancement scan before treatment. According to the recurrence by 1 year of follow-up after treatment,patients were divided into recurrence group and non-recurrence group. The influencing factors of recurrence in HCC patients after interventional therapy were analyzed by univariate analysis and multivariate Logistic regression analysis. The predictive value of MSCT en-hancement scan in recurrence of HCC patients after interventional therapy was analyzed by receiver operating characteristic (ROC) curves. Results:In the 102 HCC patients after interventional therapy,there were 37 cases (36.27％) with recurrence within 1 year of follow-up. According to the recurrence by 1 year of follow-up,patients were divided into recurrence group (n=37) and non-recurrence group (n=65). There was no significant difference in tumor diameter,tumor sites,enhancement rates in arterial and venous phases,age,gender,history of hepatitis B,cirrhosis,AFP,ALT,TBiL and ALB between the two groups (P>0.05),but there were significant differences in enhancement sign,tumor morphology,envelope types and AST (P<0.05). Lo-gistic regression analysis showed that preoperative enhancement sign in MSCT enhancement scan,continuous multinodular mor-phology and no envelope were independent risk factors of recurrence in HCC patients (P<0.05). The results of ROC curves analysis showed that area under the curve (AUC),sensitivity and specificity of enhancement sign,tumor morphology and enve-lope type for predicting the recurrence in HCC patients at 1 year after interventional therapy were 0.601,64.86％,55.38％;0.644,51.35％,75.38％;0.725,81.08％,53.85％,respectively(P<0.05). Conclusion:Preoperative enhancement sign in MSCT enhancement scan,continuous multinodular morphology and no envelope are independent risk factors of recurrence in HCC patients within 1 year of follow-up after treatment. MSCT enhancement scan has certain reference value in predicting recur-rence of HCC patients after interventional therapy.
万方数据
维普
