Objective:To summarize the imaging characteristics of 18F-FDG PET/CT and CT in aggressive fibromatosis(AF) and evaluate its application value. Methods:The clinical data,CT plain scan,enhanced scan,and 18F-FDG PET/CT findings of 27 cases diagnosed with AF were retrospectively analyzed. Results:A total of 37 lesions from 27 patients with AF were included,most of these were solitary. Intra-abdominal type was more common. First symptoms of the disease appeared inci-dentally during imaging examination or physical examination. Tumor proliferation antigen marker Ki-67 was 3％(2％～5％). All the lesions showed FDG uptake,which showed slightly or moderately uptake,with relatively high uptake in the inner or slightly uniform uptake. Even if the larger lesion did not increase significantly in maximum standardized uptake value (SU-Vmax),which ranged from 1.40 to 5.10,with an average value of 3.32±1.12. There were no significant differences in SUVmax of different lesion locations. Most lesions presented as soft tissue masses with expansion growth type on CT scanning,which were round-like,incomplete envelope. The boundaries of most of the lesions were not clear. The lesions presented as relative-ly uneven. There were rarely present with calcification,cystic changes,hemorrhage or fat. AF in different locations of onset showed diverse CT manifestations. The intra-abdominal AF was easy to infiltrate the abdomino-pelvic organs and surrounding tissues,especially tubular structures. The extra-abdominal AF was smooth. The abdominal wall AF growed along the long axis of the muscle,and the lesions were relatively larger. The enhanced CT images showed progressive enhancement. Mild to mod-erate unifom or non-unifom reinforcement was observed. Some lesions showed tortuous vascular shadows inside or at the edges in the arterial phase. Conclusion:The combined application of 18F-FDG PET/CT and CT can provide diagnosis and differen-tial diagnosis information of AF.
国家科技期刊平台
NSTL
万方数据
