Effect of tai chi on NO,ET-1 and hs-CRP in middle-aged and elderly patients with asymptomatic cerebral infarction
Objective To observe the effect of Tai Chi exercise on the levels of nitric oxide(NO),endothelin-1(ET-1)and high-sensitivity C-reactive protein(hs-CRP)in patients with asymptomatic cerebral infarction(SBI).Methods From March 2021 to May 2023,147 patients diagnosed with SBI in the Health Management Center(Preventive Treatment of Disease)of the Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine were selected.They were randomly divided into 3 groups,49 cases in each group.The health education group was given health education on SBI-related knowledge.On the basis of the health edu-cation group,the Tai Chi group and the brisk walking group were given 24-style simplified Tai Chi training and brisk walking training respectively,3 times a week,60 minutes each time,for 12 weeks.After 12 weeks,the levels of NO,ET-1 and hs-CRP in the three groups were observed before and after intervention.Results ①The results of repeated measures analysis of variance showed that the time effect,inter-group effect and interaction effect of NO in the three groups were statistically significant(P<0.05).The time effect and interaction effect of ET-1 in the three groups were statistically significant(P<0.05),and there was no significant difference be-tween the groups(P>0.05).There was no significant difference in the time effect,inter-group effect and interaction effect of hs-CRP among the three groups(P>0.05).②Compared with before intervention,the level of NO in the Taichi group increased after inter-vention,and the levels of ET-1 and hs-CRP decreased.The level of ET-1 in the brisk walking group decreased,and the difference was statistically significant(P<0.05).③The results of comparison between groups after intervention showed that the NO level after in-tervention in the Taichi group was higher than that in the brisk walking group and the health education group,and the difference was statistically significant(P<0.05).The level of ET-1 in the health education group after intervention was higher than that in the Tai-chi group and the brisk walking group(P<0.05).The hs-CRP level after intervention in the Taichi group was lower than that in the brisk walking group,and the difference was statistically significant(P<0.05).Conclusion Taichi can increase NO synthesis and reduce the release of ET-1 and hs-CRP in patients with SBI.
万方数据
维普
