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应激性血糖升高比值与老年卒中相关性肺炎的相关性分析

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目的 探讨应激性血糖升高比值(SHR)与老年卒中相关性肺炎(SAP)的相关性.方法 收集 2019 年 2 月至2021 年2 月在河南省人民医院神经内科ICU住院的合并SAP的缺血性脑卒中老年患者48 例和未合并SAP的老年脑卒中患者72 例,分别为SAP组和对照组.统计两组的一般资料及入住ICU时的糖化血红蛋白(HbA1c)和空腹血糖,计算其应激性高血糖比值(SHR).根据随访患者28 天预后情况,将SAP组分为预后良好组(n =27)与预后不良组(n =21);多因素Logistic回归及ROC曲线分析SHR与SAP的相关性及诊断价值.结果 SAP组SHR比值显著高于对照组(P<0.05);预后良好组患者的年龄、FBG、SHR、吞咽障碍、脑卒中史、留置导管、意识障碍、机械通气以及NIHSS评分均低于预后不良组(P<0.05).Logistic回归分析显示,SHR、年龄、吞咽困难、房颤以及NIHSS评分是SAP的危险因素(P<0.05);机械通气、FBG、SHR及NIHSS评分是影响 SAP预后的危险因素(P<0.05).SHR诊断 SAP 及其预后的 ROC 曲线下面积分别为0.797 及0.790(95%CI 0.713~0.865 及 95%CI 0.648~0.894),诊断敏感性分别为 83.33%及 85.71%,特异性分别为69.44%及66.67%.结论 SHR对于老年脑卒中SAP的发生及其预后具有一定预示意义,临床可通过检测患者入院时SHR以辅助评估患者SAP的发病风险及监测预后.
Correlation analysis of stress elevated blood glucose ratio and senile stroke-associated pneumonia
Objective To investigate the relationship between stress hyperglycemia(SHR)and stroke-associated pneumonia(SAP)in elderly patients with stroke.Methods From February 2019 to February 2021,48 elderly patients with ischemic stroke complicated with SAP were selected as the SAP group,and 72 stroke patients without SAP were selected as the control group in the Neurology ICU of Henan Provincial People's Hospital.The general information,glycosylated hemoglobin(HbA1c)and fasting blood glucose of the two groups at admission to ICU were recorded,and the stress hyperglycemia(SHR)was calculated.According to the follow-up of patients with 28 days prognosis,divided into good prognosis group(n =27)and poor prognosis group(n =21).Multivari-ate Logistic regression and ROC curve were used to analyze the correlation and diagnostic value of SHR with SAP.Results The ratio of SHR in SAP group was significantly higher than that in control group(P<0.05).The age,FBG,SHR,dysphagia,stroke history,indwelling catheter,disturbance of consciousness,mechanical ventilation and NIHSS score of patients in the good prognosis group were lower than those in the poor prognosis group(P<0.05).Logistic regression analysis showed that SHR,age,dysphagia,atrial fi-brillation and NIHSS score were risk factors for SAP(P<0.05).Mechanical ventilation,FBG,SHR and NIHSS score were risk fac-tors affecting the prognosis of SAP(P<0.05).The ROC AUC of SHR for SAP diagnosis and prognosis were 0.797 and 0.790(95%CI =0.713~0.865 and 95%CI =0.648~0.894),respectively and the diagnostic sensitivity was 83.33%and 85.71%,and the specificity was 69.44%and 66.67%.Conclusion SHR has a certain predictive value for the occurrence and prognosis of SAP in elderly stroke patients.Clinical detection of SHR at admission can be used to evaluate the risk of SAP and monitor the prognosis of patients.

ratio of stress hyperglycemiaischemic strokestroke-associated pneumonia

王华丽、陈云霞

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河南省人民医院神经内科ICU 450003

应激性血糖升高比值 缺血性脑卒中 卒中相关性肺炎

2024

中国老年保健医学
中国老年保健医学研究会

中国老年保健医学

影响因子:0.637
ISSN:1672-4860
年,卷(期):2024.22(1)
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