Correlation analysis between atrial fibrillation type and left atrial appendage thrombosis in female patients with non-valvu-lar atrial fibrillation
Objective To investigate the relationship between the type of atrial fibrillation(AF)and the formation of left atrial thrombus in female patients with non-valvular AF.Methods A total of 305 female patients with non-valvular atrial fibrillation who were hospitalized in the department of cardiology of Guizhou Provincial People's Hospital from October 2019 to February 2022 were retrospectively analyzed.The clinical baseline data and auxiliary examination results of the patients were collected.According to the results of transesophageal echocardiography,the patients included in the study were divided into the left atrial appendage without thrombosis group(n =260)and the left atrial appendage with thrombosis group(n =45).The baseline data of the two groups were compared,and Logistic regression analysis was used to explore the predictive factors of left atrial appendage thrombosis in female pa-tients with non-valvular atrial fibrillation.Results A total of 305 female patients with non-valvular AF were included,45 of them(15%)had left atrial thrombus.There were no significant differences in age,left ventricular ejection fraction(LVEF),plasma fi-brinogen concentration(Fbg),and the proportion of hypertension,coronary atherosclerotic heart disease,vascular disease,and stroke between the two groups(P>0.05).The duration of AF,CHA2DS2-VASc score,left atrial diameter(LAD),left ventricular end-di-astolic diameter(LVEDD),B-type natriuretic peptide(BNP),serum creatinine(SCr),and the proportion of non-paroxysmal AF,type 2 diabetes,and heart failure in the left atrial thrombus group were higher than those in the left atrial no thrombus group(P<0.05),while the proportion of patients with diabetes and heart failure in the left atrial thrombus group was lower than that in the left atrial no thrombus group(P<0.05).After adjusting for confounding factors,non-paroxysmal AF was an independent predictor of left atrial thrombus formation in female patients with non-valvular AF(OR =0.252,95%CI 0.114～0.557,P =0.001).Conclu-sion Non-paroxysmal AF is an independent predictor of left atrial thrombus formation in female patients with non-valvular AF.
万方数据
维普
