首页|膳食补充剂辅助治疗高尿酸血症的研究进展

膳食补充剂辅助治疗高尿酸血症的研究进展

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高尿酸血症容易增加患者患痛风、心血管疾病、代谢性疾病的风险.膳食补充剂因其安全有效性已广泛应用于全球健康人群和各类疾病患者.本文归纳整理了膳食补充剂降低尿酸的流行病学研究和临床试验文献,分析了补充维生素和维生素原、矿物质和微量元素、氨基酸、植物制剂和植物提取物、其他营养补充剂等五类膳食补充剂辅助治疗高尿酸血症的疗效,为高尿酸血症患者安全、合理地应用膳食补充剂提供参考.研究发现,膳食补充剂用于预防和辅助治疗高尿酸血症有着十分广阔的应用前景,使用植物制剂和植物提取物以及益生菌、富氢水等新型膳食补充剂对高尿酸血症患者进行辅助治疗,可以辅助患者更好的降低尿酸水平.然而,目前只有少数膳食补充剂进入临床试验,大多数仍在动物实验阶段.
Progress in the study of dietary supplements for the adjunctive treatment of hyperuricemia
Hyperuricaemia increases the risk of gout,cardiovascular disease,and metabolic disease in patients.Dietary supple-ments are widely used in healthy populations and patients with various diseases worldwide due to their safety and efficacy.This article summarizes epidemiological studies and clinical trials on the use of dietary supplements to reduce uric acid.It analyses the efficacy of five types of dietary supplements,including vitamins and pro-vitamins,minerals and trace elements,amino acids,botanicals and plant extracts,and other nutritional supplements,in the adjuvant treatment of hyperuricemia.The aim is to provide a reference for the safe and rational application of dietary supplements in patients with hyperuricemia.The study found that dietary supplements have a very broad application prospect for the prevention and adjuvant treatment of hyperuricemia.The use of phytochemicals and plant extracts,as well as probiotics and hydrogen-rich new dietary supplements in the adjuvant treatment of patients with hyperuricemia can help patients to better reduce uric acid level.However,only a few dietary supplements have entered clinical trials and most are still in the animal experimental stage.

hyperuricemiadietary supplementsclinical trialsadjuvant therapyresearch progress

吴逢霖、张家硕、江雪、秦树存、薛雅卓、刘伯言

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山东第一医科大学第二附属医院泰山氢生物医学研究院 271000

山东第一医科大学(山东省医学科学院)护理学院 271000

泰山护理职业学院 271000

青岛大学附属泰安市中心医院氢医学研究中心 271000

青岛滨海学院 266000

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高尿酸血症 膳食补充剂 临床试验 辅助治疗

国家自然科学基金山东省高等学校青创科技支持计划山东第一医科大学学术提升计划

822005082023KJ1842019QL010

2024

中国老年保健医学
中国老年保健医学研究会

中国老年保健医学

影响因子:0.637
ISSN:1672-4860
年,卷(期):2024.22(3)
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