目的 通过Meta分析评估我国老年共病患者衰弱的患病率.方法 系统检索PubMed、Web of science、Embase、Cochrane Library、CINAHL、中国知网、万方数据库、维普网和中国生物医学文献数据库,检索时限为从建库至2024年3月5日.采用Stata15.0软件进行Meta分析.结果 共纳入23篇文献,共包括12604例老年共病患者.Meta分析结果显示,老年共病患者衰弱患病率为39.7％(95％CI 34.2％～45.3％).亚组分析结果显示,衰弱患病率随着年龄的增长递增,且具有认知障碍的老年共病患者衰弱患病率更高;样本量＜300人比样本量≥300人的患病率高,采用Tilburg衰弱评估量表进行衰弱调查的患病率最高、Fried衰弱表型评估量表次之、Frail衰弱筛查量表最低(均P＜0.01).结论 当前证据显示,我国老年共病患者衰弱患病率为39.7％,其中年龄≥80岁、具有认知障碍的人群患病率更高,应当重视对该人群衰弱的早期筛查与管理,从而延缓或防止衰弱的发生.
The prevalence of frailty in elderly patients with multimorbidity:a Meta-analysis
Objective To evaluate the prevalence of frailty in elderly patients with multimorbidity in China by Meta-analysis.Methods PubMed,Web of science,Embase,Cochrane Library,CINAHL,CNKI,Wanfang Data,VIP and China Biology Medicine Disc were searched from inception to 3Mar 5th,2024.Stata 15.0 software was used for Meta-analysis.Results Included in the total of 23 articles,including 12 604 cases of elderly patients.The results of Meta-analysis showed that the prevalence of frailty was 39.7％(95％CI 34.2％～45.3％).The results of subgroup analysis showed that the prevalence of frailty increased with age,and the prevalence was higher in the elderly comorbid with cognitive impairment.The prevalence of frailty in the sample size＜300 was higher than that in the sample size ≥ 300.The prevalence of frailty in the Tilburg Frailty scale was the highest,followed by Fried Frailty phenotype scale and FRAIL was the lowest(all P＜0.01).Conclusion Current evidence shows that the prevalence of frailty in eld-erly patients with comorbidities in China is 39.7％,and the prevalence is higher in people aged ≥80 years and with cognitive im-pairment.We should pay attention to early screening and management of frailty in this population,so as to delay or prevent the occur-rence of frailty.
万方数据
维普
