首页|半夏厚朴汤治疗气郁痰阻型胃食管反流病老年患者的临床疗效

半夏厚朴汤治疗气郁痰阻型胃食管反流病老年患者的临床疗效

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目的 观察半夏厚朴汤治疗气郁痰阻型胃食管反流病老年患者的临床疗效.方法 将60例气郁痰阻型胃食管反流病老年患者随机分为观察组和对照组,每组30例.对照组予以口服埃索美拉唑镁肠溶片和氟哌噻吨美利曲辛片治疗,观察组予以口服埃索美拉唑镁肠溶片和半夏厚朴汤加减,疗程8周,比较治疗前后以及两组患者临床症候积分、汉密尔顿抑郁量表-17(HAMD-17)和汉密尔顿焦虑量表-14(HAMA-14)、心率变异性(Heart Rate Variability,HRV)指标.结果 两组患者治疗后临床症候积分、HAMD-17评分、HAMA-14评分、HRV指标较治疗前均有显著变化(P<0.01),组间比较HRV指标低频(Low Frequency,LF)和LF/HF差异具有显著性(P<0.05).结论 半夏厚朴汤加减联合埃索美拉唑镁肠溶片治疗气郁痰阻型、老年性胃食管反流病患者,可显著改善患者的主要症状,并减轻患者的不良情绪.
Clinical effect of banxia Houpo decoction in the treatment of senileacid reflux disease patients with Qi-stagnation syndrom
Objective To observe the clinical efficacy of Banxia Houpo Decoction on senile gastroesophageal reflux disease(GERD)with Qi stagnation and phlegm obstruction.Methods 60 patients were randomly divided into the observation group and the control group,with 30 cases in each group.The control group was treated with oral esomeprazole magnesium enteric coated tablets and droperidol tonmelitracin tablets,while the observation group was treated with oral esomeprazole magnesium enteric coated tablets and modified Banxia Houpo Decoction for 8 weeks.Clinical symptom scores,Hamilton Depression Scale-17(HAMD-17),Hamilton Anxiety Scale-14(HAMA-14),and Heart Rate Variability(HRV)indicators were compared before and after treatment,as well as between the two groups of patients.Results After treatment,the clinical symptom score,HAMD-17 score,HAMA-14 score,and HRV indicators of the two groups of patients showed significant changes compared to before treatment(P<0.01).There was a sig-nificant difference in HRV indicators between the groups,including Low Frequency(LF)and LF/HF(P<0.05).Conclusion The combination of modified Banxia Houpo Decoction and esomeprazole magnesium enteric coated tablets can significantly improve the main symptoms of elderly GERD patients with Qi Stagnation and Phlegm Obstruction,and alleviate their negative emotions.

gastroesophageal reflux diseasebanxia houpo tangthe agedanxiety and depression stateheart rate variability

修春英、曾屹生

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福建中医药大学附属康复医院 350003

福建省康复技术重点实验室 350003

福建中医药大学附属第二人民医院 350003

胃食管反流病 半夏厚朴汤 老年人 焦虑、抑郁状态 心率变异性

2024

中国老年保健医学
中国老年保健医学研究会

中国老年保健医学

影响因子:0.637
ISSN:1672-4860
年,卷(期):2024.22(4)