Keloid is a kind of pathological scar,when the skin is damaged,the lesion area extends beyond the boundary of the original lesion and higher than the normal skin surface,in addition it will not disappear spontaneously over time.The pathogenesis of keloid is very complicated to study.Currently,the main causes include excessive proliferation of fibroblasts,excessive deposition of collagen and extracellular matrix,and excessive generation of blood vessels.Traditional treatment methods are mainly composed of surgical treatment,but the postoperative recurrence rate is extremely high.According to the different clinical characteristics of keloid,many treatments have been derived.This article will review the progress of keloid treatment from surgical treatment,physical therapy,drug treatment and biological therapy,hoping to bring enlightenment to the future clinical work.
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