Progress in the Treatment of Pathological Scars by Injection Therapy
The healing of skin wounds is a relatively complex biological process that involves the joint coordination of multiple cells,including fibroblasts and macrophages,at different stages of healing,including cell migration and proliferation,vascular regeneration,extracellular matrix deposition and remodelling.Abnormal healing at any stage of the repair process can lead to the development of pathological scarring,which can be clinically classified as proliferative scarring or keloid scarring depending on the duration of the pathological scar,the arrangement of collagen within the scar tissue,and whether it invades the surrounding normal skin.Current treatment options include intra-focal injection therapy,surgical excision and radiation therapy.The advantages and feasibility of injection therapy have been further enhanced with the development of pharmacological and cytokine research,as well as the development of a variety of complementary injection tools and techniques.This article reviews the latest advances in injection therapy for pathological scarring during wound healing.
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维普
