Clinical Efficacy of the Treatment of Wagner Classification 2-4 Diabetic Foot Wound with the Combination of PRP Local Injection and Local Oxygen Therapy
Objective To observe the clinical effect of the treatment of Wagner classification 2-4 diabetic foot wound with the combination of PRP local injection and local oxygen therapy.Methods A retrospective study was conducted on the clinical data of 87 patients with diabetic foot(Wagner grade 2 to 4)admitted to the author's hospital from January 2019 to December 2021.The patients were divided into control group(42 cases)and PRP group(45 cases)according to different treatment methods.The wounds in the control group were treated with routine treatment and local oxygen therapy.The PRP group was treated with PRP local injection on the basis of the treatment of the control group.The inflammatory index,pain score,wound healing rate,and wound healing time of the two groups were statistically compared.Results After 3 weeks of treatment,the inflammatory indexes(white blood cell,C-reactive protein,erythrocyte sedimentation rate,procalcitonin)in PRP group were lower than those in control group(P＜0.05),the pain VAS score in PRP group was lower than that in control group(P＜0.05),and the wound healing rate in PRP group was higher than that in control group(P＜0.05).The wound healing time in PRP group was shorter than that in control group(P＜0.05).Conclusion All data showed that diabetic foot wound healing time was accelerated,the wound healing rate was improved and the wound healing time was shorted after treatment with the combination of PRP local injection and local oxygen therapy.
万方数据
维普
