Effect Observation of Human Epidermal Growth Factor Combined with Tranexamic Acid on Melasma Treated by Electromagnetic Wave
Objective To observe the effect of electromagnetic wave introduction of human epidermal growth factor combined with tranexamic acid in the treatment of melasma.Methods Selected 90 cases of melasma patients in the author's hospital from January 2021 to April 2022 as the research object,the patients were randomly divided into 3 groups.Group A was introduced into human epidermal growth factor with electromagnetic wave,group B was introduced into tranexamic acid with electromagnetic wave,and group C was introduced into human epidermal growth factor combined with tranexamic acid with electromagnetic wave,30 cases each,and treated once a week for 3 months.The score of melasma area and severity index(MASI),the feature counts of spots,ultraviolet spots,brown spots and red areas of VISIA were compared before and after treatment,and the satisfaction of patients was investigated.Results After the treatment of the three groups of patients,the MASI scores were reduced,and the difference between the three groups was statistically significant,and the MASI scores of Group C were lower than those of Groups A and B(P＜0.001).The difference between the efficacy between the three groups before and after treatment was statistically significant,and the efficacy of group C was significantly better than that of the other two groups(P＜0.05).The feature counts of VISIA include spots,UV spots,brown spots and red areas all decreased after treatment in group C were all reduced after treatment(all P＜0.05).The satisfaction rate of group C after treatment was the highest(96.67%),and the difference of satisfaction rate among the three groups was statistically significant(P＜0.05).Conclusion Electromagnetic wave introduction of human epidermal growth factor combined with tranexamic acid in the treatment of melasma is safe and effective.
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