Risk of Postoperative Recurrence of Pterygium and Its Correlation with Disease Characteristics
Objective To explore the risk of postoperative recurrence of pterygium and its correlation with the characteristics of the disease.Methods From March 2017 to March 2022,189 patients with pterygium in the author's hospital were taken as the research object.All patients underwent pterygium excision and limbal stem cell transplantation.Collect the general information and disease characteristics of all patients.All patients were followed up for one year after operation.According to whether there was recurrence after operation,the patients were divided into recurrence group and non-recurrence group.Multivariate Logistic regression was used to analyze the related factors affecting the recurrence of the two groups.The resected tissues were collected and the vascular endothelial growth factor(VEGF)was detected by immunohistochemical method.Pearson correlation was used to analyze the correlation among relative length RL,relative width RW,relative area RA and Vascularization index Ⅵ of pterygium.Results After the follow-up,there were 7 lost cases,and finally 182 cases were included in the study.There was no significant difference in sex,comorbidity,smoking,drinking and family history between the two groups(P＞0.05).There were significant differences in pterygium RL,RW,RA,VI and vascular endothelial growth factor(VEGF)between two groups(P＜0.05).Multivariate Logistic regression results showed that VEGF[OR=0.695,95％CI(0.568,0.851)],RL[OR=0.920,95％CI(0.876,0.966)],RA[OR=0.871,95％CI(0.784,0.969)]and VI[OR=0.911,95％CI(0.867,0.957)].Pearson correlation analysis showed that there was a positive correlation among RL,RW,RA and VI(P＜0.05).Conclusion There is a positive correlation between RL,RW,RA and VI of pterygium,and RL,RW,VI and VEGF are related factors affecting the recurrence of pterygium after operation.
pterygiumrecurrencecharacteristics of illnessvascular endothelial growth factorcorrelation
国家科技期刊平台
NSTL
万方数据
维普
