Effects of Silver Ion Dressing Combined with Compound Polymyxin B Ointment in the Treatment of Deep Second-Degree Burn Infectious Wounds
Objective To explore the effects of silver ion dressing and compound polymyxin B ointment in the treatment of burn infectious wounds.Methods A total of 149 patients with deep partial-thickness burn infection wounds were selected and divided into observation group(n=75)and control group(n=74)according to the random number table method.The control group was treated with compound polymyxin B ointment,and the observation group was treated with silver ion dressing on the basis of the control group.The wound recovery related indicators,wound pain degree,serum inflammatory factors and pain mediators levels,clinical efficacy and scar condition were statistically compared between the two groups.Results After treatment,the infection control time,hospitalization time,and wound healing time in the observation group were shorter than those in the control group(P＜0.05),and the wound healing rate after 21 days of treatment was higher than that in the control group(P＜0.05).The pain scores of the observation group were lower than those of the control group at each time point after treatment(P＜0.05).After 21 days of treatment,the serum levels of C-reactive protein,interleukin-6,neuropeptide Y,and prostaglandin E2 in the observation group were lower than those in the control group(P＜0.05),and the total effective rate of wound healing was higher than that in the control group(P＜0.05).Six months after wound healing,each score and total score of Vancouver Scar Scale in the observation group were lower than those in the control group(P＜0.05).Conclusion Silver ion dressing combined with compound polymyxin B ointment in the treatment of deep partial-thickness burn infected wounds can promote wound healing,reduce wound pain,effectively inhibit the levels of serum inflammatory factors and pain mediators,reduce wound scar,and improve wound aesthetic effect.
silver ion dressingcompound polymyxin b ointmentdeep second-degree burn infectious woundsinflammatory factorsscar
国家科技期刊平台
NSTL
万方数据
维普
