Correlation Analysis of Dermoscopic Features and Photodynamic Treatment Effect in Patients with Actinic Keratosis
Objective To investigate the correlation between the dermoscopic features of actinic keratosis(AK)and the therapeutic effect of photodynamic therapy(PDT).Methods A total of 82 AK patients who received PDT treatment in the author's hospital from June 2021 to September 2022 were selected as the study objects.All subjects underwent dermoscopy before inclusion.All subjects cleaned their facial skin and were illuminated by photodynamic therapy apparatus.They were irradiated for 1-6 times according to the patients'conditions.Results Among the 82 patients,male accounted for 71.95%,most of the lesions were located in the temporal part,Olsen clinical classification of AK grade 1 31.71%,AK grade 11 54.88%,AK grade Ⅲ 13.41%.The average number of PDT treatment of the 82 patients was(2.29±0.69)times.After treatment,50 patients had complete remission,the disappearance of pathological changes was complete remission,23 patients had partial remission,and the total effective rate of PDT treatment was 89.02%.After treatment,the positive rates of scales,hair follicle orifice and red pseudoreticular structure were significantly decreased(P<0.05).Conclusion PDT is effective in the treatment of AK patients,and the patients with scaly,hair follicle orifice and red pseudoreticular structure are more beneficial in the treatment of PDT.