脂肪干细胞外泌体提高脂肪移植存活率的研究进展
Research Progress of Adipose Stem Cell Exosomes to Improve the Survival Rate of Fat Transplantation
尹从洋 1公美华 2邹同荣 3谢林海2
作者信息
- 1. 赣南医学院第一临床医学院 江西赣州 341000
- 2. 赣南医学院第一附属医院整形外科 江西赣州 341008
- 3. 宜宾市第一人民医院整形烧伤科 四川宜宾 644000
- 折叠
摘要
脂肪移植是外科治疗组织缺损、凹陷的重要治疗手段,脂肪细胞具有来源丰富、良好的组织相容性等优点,成为了整形外科治疗的一个重要手段.但是,传统的脂肪移植存在移植物存活率低、术后效果不稳定等局限,随着细胞辅助脂肪移植的发展,脂肪移植的存活率有了一定的提高,却没有根本解决高吸收率的问题,且可能存在致瘤等潜在风险.脂肪干细胞外泌体的发现有望改变这一现状.
Abstract
Fat transplantation is an important surgical treatment for tissue defects and depressions.Adipocytes have the advantages of abundant sources and good histocompatibility,and become an important method for plastic surgery.However,traditional fat transplantation has limitations such as low graft survival rate and unstable postoperative effect.With the development of cell-assisted fat transplantation,the survival rate of fat transplantation has been improved to a certain extent,but the problem of high absorption rate has not been fundamentally solved.Potential risks such as possible tumorigenesis.The discovery of adipose stem cell exosomes is expected to change this situation.
关键词
外泌体/脂肪干细胞/脂肪移植/炎症/血管化Key words
exosome/adipose-derived stem cells/fat transplantation/inflammation/vascularization引用本文复制引用
基金项目
江西省卫生健康委科技项目(202310051)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据