Clinical Observation of Platelet-rich Plasma Combined with 2 940 nm Fractional Erbium Laser In Treatment of Female Pattern Alopecia
Objective To explore the clinical effect of platelet-rich plasma combined with 2 940 nm fractional erbium Laser in the treatment of female pattern alopecia.Methods From May 2022 to May 2023,90 female patients with alopecia who were admitted to the dermatology department of Tianjin Beichen Hospital were selected and divided into Group A,Group B,and Group C,with 30 patients in each group.Group A was treated with platelet-rich plasma combined with 2 940 nm fractional erbium laser therapy,Group B was treated with minoxidil combined with 2 940 nm fractional erbium laser therapy,and Group C was treated with only 2 940 nm fractional erbium laser therapy.The clinical efficacy,satisfaction,adverse reactions,subjective symptoms before and after treatment(oiliness,itching,dandruff,and hair loss),and trichoscope indicators(average hair density,average vellus hair ratio,average hair shaft diameter)of patients in each group were observed and recorded.Results The clinical treatment efficiency of Group A patients(93.33%)was significantly higher than that of Group B(73.33%)and Group C(66.67%)(P＜0.05).Compared to pre-treatment,the scores of subjective symptoms such as oiliness,itching,dandruff,and alopecia were reduced in all three groups(A,B,and C)after treatment(P＜0.05),and the scores of these symptoms in Group A were lower than those in Groups B and C(P＜0.05).Compared to pre-treatment,the proportion of vellus hairs decreased,while hair density and hair shaft diameter increased in all three groups after treatment(P＜0.05).Moreover,Group A had a lower proportion of vellus hairs and higher hair density and hair shaft diameter compared to Groups B and C(P＜0.05).The overall satisfaction of Group A patients after treatment(96.67%)was significantly higher than that of Groups B(76.67%)and C(73.33%)(P＜0.05).However,there was no statistically significant difference in adverse reactions among the three groups(P＞0.05).Conclusion The combination of platelet-rich plasma and 2 940 nm fractional erbium laser therapy for female alopecia can achieve better clinical efficacy,improve scalp symptoms,increase hair density and hair shaft diameter,and has high safety.It is worthy of clinical promotion.
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