Research Progress of Percutaneous Local Anesthesia and Transdermal Drug Delivery Techniques
As a non-invasive method,transdermal drug delivery(TDD)can overcome the disadvantages of the discomfort caused by traditional injection and the first pass elimination effect via liver,and has the advantages of convenience,safety,painlessness.Recently,with the in-depth mechanical research of the transdermal penetration and the update iteration of TDD technology,various local anesthesia preparations and TDD techniques have emerged endlessly.This paper outlines the local anesthesia drugs,the technical progress of TDD,and the future exploration direction of them,providing a reference for the research in the field of local anesthesia.
local anesthesiatransdermal drug deliverypercutaneous penetrationcosmetic dermatologylidocaine
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