Q-switched lasers are widely used for tattoo removal,with standardized treatment protocols.However,long treatment period,high risk of complications,as well as the instable efficacy of this technique cannot be ignored.To overcome the limitations of Q-switched laser in tattoo removal,some new treatment strategies had emerged recently,including picosecond laser,Q-switched lasers combined with drugs or other lasers,repeated treatment of Q-switched lasers(R20 and R0).Among them,Q-switched lasers combined with other lasers,especially the fractional carbon dioxide laser,outperformed other treatment options and had a brighter future of further clinical application.Therefore,new advance in laser tattoo removal were summarized and the combination of Q-switched laser and fractional carbon dioxide laser in tattoo removal was detailed in this paper.