Application of Negative Pressure Wound Therapy Combined with Scab Removal and Skin Grafting in the Repair of Deep Burn Wounds
Objective To explore the repair effect of negative pressure wound therapy(NPWT)combined with scab removal and skin grafting in wound after deep burn.Methods A total of 112 patients with deep burns admitted to the author's hospital from January 2020 to January 2023 were selected and divided into experimental group(56 cases)and control group(56 cases)according to the random number table method.The control group was treated with tangential excision and skin grafting,and the experimental group was treated with NPWT combined with tangential excision and skin grafting.The clinical efficacy,wound healing,pain score[visual analogue scale(VAS)],appearance satisfaction score,inflammatory factor level[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)],complications and scar condition[Vancouver scar scale(VSS)]were compared between the two groups.Results After treatment,the clinical efficacy of the experimental group was better than that of the control group,and the wound healing time was shorter than that of the control group,and the differences were statistically significant(P＜0.05).At 7 days after skin grafting,the wound healing rate,skin graft survival rate,and appearance satisfaction score of the experimental group were higher than those of the control group(P＜0.05),and the pain VAS score,TNF-α and IL-6 levels were lower than those of the control group(P＜0.05).During the treatment,the total incidence of complications in the experimental group was lower than that in the control group(P＜0.05).At 6 months after skin grafting,the scores and total scores of VSS in the experimental group were lower than those in the control group(P＜0.05).Conclusion Repair effect of NPWT combined with scab removal and skin grafting is good in wound after deep burn,which can effectively promote wound healing,relieve pain,reduce scar formation,and improve prognosis of patients,which is worthy of clinical application.
国家科技期刊平台
NSTL
万方数据
