首页|耳垂瘢痕疙瘩的形成机制及临床治疗研究进展

耳垂瘢痕疙瘩的形成机制及临床治疗研究进展

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瘢痕疙瘩是机体对真皮损伤的过度组织反应,发生于真皮网状层,表现为超出原始创面边界并侵入周围健康皮肤的隆起性真皮病灶.最突出的特征是成纤维细胞增殖及细胞外基质的广泛沉积.瘢痕疙瘩常见于上胸部、肩部、后背上方以及头颈部,在头颈部时尤其好发于耳朵,会随着时间进行性增大,常伴随疼痛及瘙痒症状,耳垂瘢痕疙瘩有多种治疗方法,但复发率都很高,在临床上如何有效控制瘢痕疙瘩的发生及复发仍然是个难题,针对耳垂瘢痕疙瘩形成机制进行深入研究,有助于确定特定的靶点途径,减少疾病的发生.对比研究耳垂瘢痕疙瘩的各种治疗手段也有助于患者选择最佳治疗方案,减少疾病复发率,提高患者术后生活质量.
Research Progress on Formation Mechanism and Clinical Treatment of Earlobe Keloid
Keloid is the body's excessive tissue response to dermal injury,often occurring in the dermis as swelled dermal lesions that extend beyond the original wound boundary and invade the surrounding healthy skin.The most prominent feature is fibroblast proliferation and extensive deposition of extracellular matrix.Keloid is frequently observed on the anterior chest,shoulders,posterior upper back,and craniofacial region,especially occured on ears when keloid grows on the head.It will gradually increase with time,often accompanied by pain and itching symptoms.Earlobe keloid has a variety of treatment methods,however,which has high recurrence rate,Conducting thorough research on the process of earlobe keloid formation can aid in identifying specific target pathways and reducing the incidence of the disease.Additionally,a comparative analysis of various treatment methods for earlobe keloid can assist patients in selecting the most effective treatment plan,reducing the likelihood of recurrence,and enhancing their quality of life after surgery.

earlobe keloidschwann cellsvascular endothelial dysfunctionsurgical operationpostoperative radiotherapydrug treatment

伍诗涵、阿地拉·阿布力孜、许辉

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新疆维吾尔自治区人民医院口腔颌面外科 新疆 乌鲁木齐 830001

新疆医科大学 新疆 乌鲁木齐 830054

耳垂瘢痕疙瘩 施万细胞 血管内皮功能障碍 外科手术 术后放疗 药物治疗

2024

中国美容医学
西安交通大学第四军医大学

中国美容医学

CSTPCD
影响因子:1.006
ISSN:1008-6455
年,卷(期):2024.33(10)
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