Objective To analyze the morphology and volume of cone-beam CT(CBCT)in patients with odontogenic jaw cysts and its correlation with clinical efficacy.Methods Eighty-three patients with odontogenic jaw cysts who were treated in the author's hospital from September 2021 to March 2022 were selected as the research subjects.CBCT was used to measure the diameter and volume of odontogenic jaw cysts,and the relationship between jaw morphology and cyst diameter and volume was analyzed.According to the clinical efficacy,the patients were divided into effective group and ineffective group,and the relationship between morphology and volume and clinical efficacy was analyzed.Results The patients with obvious clinical symptoms,multi-locular morphology,irregular shape edge and excessive bone mass of odontogenic jaw cysts had larger cyst diameter and volume(P<0.05).According to the treatment situation after three months,49 cases were included in the effective group and 34 cases were included in the ineffective group.The multi-locular morphology,the proportion of irregular margin,and the diameter and volume of cysts in the ineffective group were higher than those in the effective group(P<0.05).Multivariate Logistic analysis showed that the age of the patient(OR=0.540,P=0.012),diameter of the cyst(OR=0.482,P=0.043),volume(OR=0.086,P=0.009),morphology(OR=3.610,P=0.031),and marginal condition(OR=3.491,P=0.024)were all relevant factors affecting the clinical efficacy(P<0.05).Conclusion Special attention should be paid to the clinical situation of patients with odontogenic jaw cysts of large diameter and outwardly expanding volume.Close morphological and volumetric clinical pathology follow-up should be conducted for patients with irregular edge morphology,multi-locular morphology,excessive bone mass and Clinical palpation showed a ping-pong sensation.