Efficacy of Fractional CO2 Laser Combined with Topical Triamcinolone Acetonide in the Treatment of Hypertrophic Scars
Objective This study aimed to evaluate the therapeutic efficacy of fractional CO2 laser combined with triamcinolone acetonide for the treatment of hypertrophic scars.Methods From October 2022 to October 2023,a total of 86 patients with hypertrophic scars were treated at the author's hospital and were randomly assigned to a control group or an observation group,with 43 patients in each group.The control group received fractional CO2 laser treatment,while the observation group received fractional CO2 laser treatment combined with triamcinolone acetonide.The two groups were compared in terms of scar recovery[itch score,Vancouver scar scale(VSS)score,visual analog scale(VAS)score],quality of life[Pittsburgh Sleep Quality Index(PSQI)and dermatology life quality index(DLQI)],as well as adverse effects and recurrence rates.Results After treatment,the observation group had significantly lower pruritus scores,VSS scores,and VAS scores compared to the control group(P＜0.05).The PSQI and DLQI scores were also significantly lower in the observation group(P＜0.05).There was no significant difference in the incidence of adverse reactions between the two groups,but the recurrence rate in the observation group was significantly lower than that in the control group(P＜0.05).Conclusion Fractional CO2 laser combined with triamcinolone acetonide demonstrates significant efficacy in the treatment of hypertrophic scars.This combination can effectively enhance scar recovery,improve patients'quality of life,and significantly reduce the recurrence rate.
fractional CO2 lasertriamcinolone acetonidehypertrophic scarpruritus score
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