Objective To assess the efficacy and safety of the combined application of micro-focused ultrasound(MFU)and injectable collagen for facial rejuvenation.Methods Ninety-six patients who visited the dermatology outpatient department at Beijing Friendship Hospital between September 2021 and June 2023 were randomly assigned to two groups:the control group(48 patients)and the combination treatment group(48 patients).The control group received only MFU treatment,while the combination group underwent MFU treatment followed by a collagen injection in the tear trough area three months post-procedure.Photographs were taken at three and four months post-MFU treatment and one month post-collagen injection.The primary outcome measures were clinical efficacy and patient satisfaction at four months post-MFU and one month post-collagen injection.Results The overall effective rate of the combination treatment group was 95.74％,and the overall satisfaction rate was 93.62％,significantly higher than those of the control group,which were 71.74％(P＜0.05)and 76.09％(P＜0.05),respectively.Conclusion The combination of micro-focused ultrasound and injectable collagen significantly improves facial rejuvenation outcomes,with minimal pain,fewer complications,and higher patient satisfaction.
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