The skin is the largest surface organ of the human body,with its structure consisting of the epidermis,dermis,and subcutaneous tissue from superficial to internal.Numerous microbial colonies are colonized on the surface of the skin and glands,was known as the skin microbiota.The skin microbiota plays a crucial role in skin health and homeostasis,and is closely related to skin aging.We have summarized the composition and role of skin microbiota,the relationship between skin microbiota and skin aging,and the application of delaying skin aging through microbiota regulation,and analyzed and explored the current research and clinical applications issues of skin microbiota and skin aging,in order to provide reference for clinical research on skin anti-aging and the development of skin microbiota products.