Traditional Chinese Medicine and Integrated Traditional Chinese and Westen Medicine in the Treatment of Subacute Thyroiditis:An Overview of Systematic Reviews
Objective To evaluate the methodological quality and outcome indicators of systematic evaluation/meta-analysis of Chinese medicine and integrated traditional chinese and westen medicine in the treatment of subacute thyroiditis.Methods Numerical criteria were developed,and electronic searches of Pubmed,Embase,Cochrane Library,China Knowledge(CNKI),China Biomedic-al Literature Database(CBM),Vip(VIP),Wanfang(WF)databases and manual searches were performed to screen out systematic evaluations/Meta-analyses of TCM treatments for subacute thyroiditis,with the search time from the construction of the database to January 18,2024.Literature screening and information extraction were performed by 2 investigators,and PRISMA 2020 statement,AMSTAR 2 tool,and GRADE grading were used to evaluate the quality of reporting,methodological quality,and quality of evidence for outcome indicators of the included studies.Results A total of 15 systematic evaluations were included,with 1 article with a PRIS-MA score ≤15 with relatively severe information deficiencies,12 articles with＞15 ≤21 with some reporting deficiencies,and 2 arti-cles with＞21 with relatively complete reporting.Evaluation of methodological quality using the AMSTAR 2 tool suggested that all 15 papers were of very low quality,mainly due to the absence of key entries caused by the lack of mention of prior protocols and the failure to provide a list of excluded papers.GRADE grading showed that of the 71 outcome indicators in the 15 papers,2 were of intermediate level of evidence,26 were of low level of evidence,and 43 were of very low level of evidence.Conclusion TCM and integrated tradi-tional chinese and western medicine treatment of SAT was shown to be effective in reducing patients'pain,shortening the time of fever reduction,and decreasing the recurrence rate.However,the quality of most of the systematic evaluation reports on TCM and integrated traditional chinese and western medicine treatment of SAT has some deficiencies,with all of them being of very low quality in terms of methodological quality,and most of the evidence on outcome indicators being of low quality.More high-quality clinical studies are still needed in the future to provide high-level evidence-based evidence for TCM treatment of SAT.
Subacute ThyroiditisTraditional Chinese MedicineCombination of Chinese and Western MedicineOverview of Systematic Review
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