Effects of Henggu Bone healing agent combined with Taohong Siwu decoction in treatment of postoperative patients with limb fractures
Objective:To observe effects of Henggu Bone healing agent combined with Taohong Siwu decoction in treatment of postoperative patients with limb fractures.Methods:The clinical data of 76 patients with limb fractures treated in this hospital from January 2020 to January 2023 were retrospectively analyzed.According to different treatment methods,they were divided into control group(37 cases)and observation group(39 cases).Both groups were treated with internal fixation.The control group was treated with Taohong Siwu decoction after the surgery,while the observation group was treated with Henggu bone healing agent on the basis of that of the control group.Both groups were treated continuously for 1 month.The clinical efficacy,the swelling regression time,the fracture healing time,the pain[visual analogue scale(VAS)]score,the limb motor function[Fugl-Meyer motor assessment(FMA)]score,the bone metabolism indexes[osteocalcin(BGP),typeⅠprocollagen carboxy terminal peptide(PⅠCP),fibroblast growth factor-2(FGF-2)]levels before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 94.87%(37/39),which was higher than 72.97%(27/37)of the control group,and the difference was statistically significant(P<0.05).The swelling regression time and the fracture healing time of the observation group were shorter than those of the control group,and the differences were statistically significant(P<0.05).After the treatment,the VAS score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).After 3 months of treatment,the FMA score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of BGP and FGF-2 in the observation group were higher than those in the control group,the level of PⅠCP was lower than that in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Henggu bone healing agent combined with Taohong Siwu decoction can improve the total effective rate and the limb motor function scores,shorten the swelling regression time and the fracture healing time,improve the levels of bone metabolism indexes and reduce the pain scores in the postoperative patients with limb fractures.Moreover,it is superior to single Taohong Siwu decoction treatment.
Limb fractureHenggu bone healing agentTaohong Siwu decoctionLimb motor functionPainBone metabolismAdverse reaction
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