Predictive value of combined detection of serum NT-proBNP and PCT levels on poor prognosis in patients with acute myocardial infarction after percutaneous coronary intervention
Objective:To investigate predictive value of combined detection of serum N-terminal pro-B-type natriuretic peptide(NT-proBNP)and procalcitonin(PCT)levels on poor prognosis of patients with acute myocardial infarction after percutaneous coronary intervention(PCI).Methods:The clinical data of 109 patients with acute myocardial infarction admitted to this hospital from February 2020 to May 2022 were retrospectively analyzed.All patients were treated with emergency PCI and followed up for 1 month,the incidence of poor prognosis was statistically analyzed.The levels of serum NT-proBNP and PCT in the patients with different prognosis and different degree of heart failure(Killip grade)were compared.The receiver operating characteristic(ROC)curve was used to analyze the predictive value of single and combined detection of serum NT-proBNP and PCT levels for poor prognosis in the patients with acute myocardial infarction after PCI.Results:There were 26 cases of poor prognosis and 83 cases of good prognosis in the 109 patients with myocardial infarction after PCI.The levels of serum NT-proBNP and PCT in the patients with poor prognosis were higher than those in the patients with good prognosis,and the differences were statistically significant(P<0.05).The higher the Killip grade was,the higher the serum NT-proBNP and PCT levels were,and the differences were statistically significant(P<0.05).ROC curve showed that the area under the curve of single NT-proBNP detection,single PCT detection and combined detection in the prediction of poor prognosis of the patients with acute myocardial infarction after PCI were 0.954,0.886 and 0.993,separately,and the sensitivity,the specificity and the Youden index of combined detection were higher than that of single index detection.Conclusions:NT-proBNP and PCT can be used as the predictors of poor prognosis for the patients with acute myocardial infarction after PCI,and the predictive value of combined detection is higher than that of single index detection.
NETL
NSTL
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