Value of coagulation indexes and 25-hydroxyvitamin D levels combined with postpartum hemorrhage prediction score in prediction of postpartum hemorrhage in women
Objective:To explore value of coagulation indexes and 25-hydroxyvitamin D[25(OH)D]levels combined with postpartum hemorrhage prediction score in prediction of postpartum hemorrhage in women.Methods:The clinical data of 123 pregnant women admitted to the hospital from March 2019 to March 2021 were retrospectively analyzed.According to whether postpartum hemorrhage occurred,they were divided into the occurrence group(65 cases)and the non-occurrence group(58 cases).The prenatal prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),fibrinogen(FIB),25(OH)D levels,and the postpartum hemorrhage prediction score were compared between the two groups.The values of single and combined prediction for postpartum hemorrhage in the pregnant women were analyzed.Results:The PT and APTT in the occurrence group were longer than those in the non-occurrence group,the FIB level was lower than that in the non-occurrence group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in TT between the two groups(P>0.05).The prenatal 25(OH)D level in the occurrence group was lower than that in the non-occurrence group,the postpartum hemorrhage prediction score was higher than that in the control group,and the differences were statistically significant(P<0.05).The receiver operating characteristic(ROC)curve showed that the area under the curve of PT,APTT,FIB,25(OH)D,postpartum hemorrhage prediction score combined prediction for postpartum hemorrhage in the pregnant women were 0.777,0.750,0.821,0.811,0.791 and 0.892,separately,and the combined prediction value was the highest.Conclusions:The value of combined prediction of PT,APTT,FIB,25(OH)D and postpartum hemorrhage prediction score in the prediction of postpartum hemorrhage in the pregnant women is higher than that of single prediction of the five.