首页|颅骨锥孔穿刺引流术与钻孔穿刺引流术治疗中等量高血压脑出血患者的效果比较

颅骨锥孔穿刺引流术与钻孔穿刺引流术治疗中等量高血压脑出血患者的效果比较

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目的:比较颅骨锥孔穿刺引流术与钻孔穿刺引流术治疗中等量高血压脑出血(HICH)患者的效果.方法:选取 2020 年1 月至 2023 年 1 月该院收治的 82 例中等量HICH患者进行前瞻性研究,以随机数字表法将其分为研究组(n=41)和对照组(n=41).研究组采用颅骨锥孔穿刺引流术,对照组采用颅骨钻孔穿刺引流术,比较两组血肿清除率、围术期指标水平,手术前后血清炎性因子[C反应蛋白(CRP)、降钙素原(PCT)、肿瘤坏死因子-α(TNF-α)]水平、神经功能缺损程度[美国国立卫生研究院卒中量表(NIHSS)]评分、日常生活能力(Barthel指数),以及术后 1 个月并发症发生率.结果:两组血肿清除率比较,差异无统计学意义(P>0.05);研究组手术时间、皮肤切口长度和住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05);术后 7、14 d,研究组血清CRP、PCT、TNF-α水平均低于对照组,差异有统计学意义(P<0.05);术后 3 个月,两组NIHSS评分均低于术前,Barthel指数均高于术前,差异有统计学意义(P<0.05),但组间比较,差异无统计学意义(P>0.05);两组并发症发生率比较,差异无统计学意义(P>0.05).结论:颅骨锥孔穿刺引流术治疗中等量HICH患者可降低围术期指标水平和血清炎性因子水平,效果优于钻孔穿刺引流术治疗.
Comparison of effects of skull conical puncture drainage and drilling puncture drainage in treatment of patients with moderate hypertensive cerebral hemorrhage
Objective:To compare effects of skull conical puncture drainage and drilling puncture drainage in treatment of patients with moderate hypertensive cerebral hemorrhage(HICH).Methods:A prospective study was conducted on 82 patients with moderate HICH admitted to this hospital from January 2020 to January 2023.They were divided into study group(n=41)and control group(n=41)by using the random number table method.The study group was treated with skull conical hole puncture drainage,while the control group was treated with skull drilling puncture drainage.The hematoma clearance rate,the perioperative index levels,the serum inflammatory factors[C-reactive protein(CRP),procalcitonin(PCT),tumor necrosis factor-α(TNF-α)]levels before and after the surgery,the neurological deficit degree[National Institutes of Health stroke scale(NIHSS)]score,the activities of daily living(Barthel index),and the incidence of complications 1 month after the surgery were compared between the two groups.Results:There was no significant difference in the hematoma clearance rate between the two groups(P>0.05).The operation time,the skin incision length and the hospitalization time of the study group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant(P<0.05).Seven and fourteen days after the surgery,the levels of serum CRP,PCT and TNF-α in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Three months after the surgery,the NIHSS scores of the two groups were lower than those before the surgery,and the Barthel indexes of the two groups were higher than those before the surgery,and the differences were statistically significant(P<0.05).but there were no significant differences between the two groups(P>0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Skull conical puncture drainage can reduce the levels of perioperative indexes and serum inflammatory factors in the patients with moderate HICH.Moreover,it is superior to skull drilling puncture drainage.

HypertensionModerateCerebral hemorrhageSkull conical hole puncture drainageSkull drilling puncture drainageInflammatory factorNeurological deficit degreeActivity of daily living

张亚军

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永城市人民医院神经外科,河南 商丘 476600

高血压 中等量 脑出血 颅骨锥孔穿刺引流术 颅骨钻孔穿刺引流术 炎性因子 神经缺损程度 日常生活能力

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(1)
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