Effects of Yiqi Shexue decoction combined with Estradiol valerate in treatment of patients with abnormal uterine bleeding
Objective:To observe effects of Yiqi Shexue decoction combined with Estradiol valerate in treatment of patients with abnormal uterine bleeding(AUB).Methods:The clinical data of 76 patients with AUB admitted to this hospital from March 2019 to March 2021 were retrospectively analyzed.According to different treatment options,they were divided into study group(n=38)and control group(n=38).The control group was treated with Estradiol valerate,while the study group was treated with Yiqi Shexue decoction on the basis of the control group.The clinical efficacy,the hemostasis time(bleeding control time,complete hemostasis time),the clinical related indicator levels[bleeding volume,endometrial thickness,hemoglobin(Hb)],the sex hormone indicator levels[follicle-stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)],and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 94.74%(36/38),which was higher than 65.79%(25/38)in the control group,and the difference was statistically significant(P<0.05).The bleeding control time and the complete hemostasis time of the study group were shorter than those of the control group,and the differences were statistically significant(P<0.05).After the treatment,the bleeding volume in the study group was less than that in the control group,the endometrial thickness was lower than that in the control group,the Hb level was higher than that in the control group,and the differences were statistically significant(P<0.05).The levels of FSH and LH in the study group were lower than those in the control group,the level of E2 was higher than that in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Yiqi Shexue decoction combined with Estradiol valerate in the treatment of the AUB patients can improve the total effective rate of treatment,shorten the hemostasis time,and improve the levels of clinical related indicators and sex hormone indicators.Moreover,it is superior to single Estradiol valerate treatment.
万方数据
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