Efficiency of quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging in differential diagnosis of breast nodules
Objective:To analyze efficiency of quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)in differential diagnosis of breast nodules.Methods:The clinical data of 68 patients with breast nodules admitted to this hospital from April 2021 to April 2023 were retrospectively analyzed.According to the results of pathological examination,they were divided into benign group(38 cases)and malignant group(30 cases).All patients underwent DCE-MRI examination.The imaging findings and the DCE-MRI quantitative parameters[rate constant(Kep),volume transfer constant(Ktrans),extravascular extracellular space volume ratio(Ve),initial area under time-concentration curve(iAUC)]were compared between the two groups.The receiver operating characteristic(ROC)curve was drawn to analyze the efficiency of single and combined detection of DCE-MRI quantitative parameters Ktrans and Ve levels in the differential diagnosis of breast nodule properties.Results:The proportions of irregular shape,burr sign on the edge,uneven internal enhancement and early enhancement rate≥60%in the malignant group were higher than those in the benign group,and the differences were statistically significant(P<0.05).The levels of Ktrans and Ve in the malignant group were higher than those in the benign group,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under the curve of single Ktrans detection,single Ve detection and combined detection in the diagnosis of breast nodules were 0.797,0.788 and 0.934,respectively,all of which had certain diagnostic value,and the combined detection had the highest diagnostic efficiency.Conclusions:The efficiency of combined detection of DCE-MRI quantitative parameters Ktrans and Ve levels in the diagnosis of breast nodules is higher than those of single detection.
Nuclear magnetic resonanceDynamic enhanced scanningBreast noduleQuantitative parameterDifferential diagnosisEfficiency
万方数据
维普
