Efficiency of contrast-enhanced ultrasound in qualitative diagnosis of bile duct space-occupying lesions
Objective:To analyze efficiency of contrast-enhanced ultrasound in qualitative diagnosis of bile duct space-occupying lesions.Methods:A prospective study was conducted on 84 patients with bile duct space-occupying lesions admitted to the hospital from July 2020 to July 2022.Contrast-enhanced ultrasound,enhanced CT and pathological examination were performed.Using the results of pathological examination as the gold standard,the efficiencies of contrast-enhanced ultrasound and enhanced CT in the qualitative diagnosis of bile duct space-occupying lesions were compared.The contrast-enhanced ultrasound imaging features and parameter levels of different types of bile duct space-occupying lesions were compared.Results:Among the 84 patients with bile duct space-occupying lesions,52 cases were diagnosed as malignant by pathological examination,all of which were cholangiocarcinoma;there were 32 benign cases including 19 cases of bile duct stones and 13 cases of bile duct cystadenoma.Contrast-enhanced ultrasonography confirmed 49 cases of malignant and 35 cases of benign.Enhanced CT examination confirmed 39 cases of malignant and 45 cases of benign.The sensitivity and the accuracy of contrast-enhanced ultrasound in the qualitative diagnosis of bile duct space-occupying lesions were higher than those of enhanced CT,the missed diagnosis rate was lower than that of enhanced CT,and the differences were statistically significant(P<0.05).The proportions of dynamic enhancement mode of malignant biliary space-occupying lesions as non-fast-in and fast-out and overall uneven enhancement in arterial phase were higher than those of benign bile duct space-occupying lesions,and the differences were statistically significant(P<0.05).The time to peak,iso-enhancement time and initial regression time of malignant bile duct space-occupying lesions were longer than those of benign bile duct space-occupying lesions,and the differences were statistically significant(P<0.05).Conclusions:The efficiency of contrast-enhanced ultrasound in the qualitative diagnosis of bile duct space-occupying lesions is higher than that of enhanced CT.
Bile duct space-occupying lesionContrast-enhanced ultrasoundEnhanced CTQualitativeDiagnosisEfficiency