Correlation between blood glucose control effect and anti-tuberculosis efficacy in patients with pulmonary tuberculosis and diabetes mellitus
Objective:To observe correlation between blood glucose control effect and anti-tuberculosis efficacy in patients with pulmonary tuberculosis and diabetes mellitus.Methods:The clinical data of 130 patients with pulmonary tuberculosis and diabetes mellitus admitted to this hospital from April 2022 to April 2023 were retrospectively analyzed.All patients were given unified hypoglycemic therapy.According to the level of blood glucose control,those patients were divided into good group,fair group and poor group.All three groups were given a unified anti-tuberculosis treatment plan.The anti-tuberculosis treatment effect,the sputum negative conversion rate,the lesion absorption rate,and the T cell subsets(CD4+,CD8+,CD4+/CD8+)levels were compared among the three groups.Results:The total effective rate of anti tuberculosis treatment of the good group was 100.00%(58/58),which was significantly higher than 82.05%(32/39)of the fair group and 66.67%(22/33)of the poor group,and the differences were statistically significant(P<0.05).The sputum negative conversion rate and the lesion absorption rate in the good group were higher than those in the fair group and the poor group,and the differences were statistically significant(P<0.05).After the treatment,the levels of CD4+ and CD4+/CD8+ in the three groups were higher than those before the treatment,those in the good group were higher than those in the fair group and the poor group,and those in the fair group were higher than those in the poor group;the levels of CD8+ in the three groups were lower than those before the treatment,that in the good group was lower than that in the fair group and poor group,that in the fair group was lower than that in the poor group;and the differences were statistically significant(P<0.05).Conclusions:The blood sugar control effect is good,and the anti tuberculosis effect of patients with pulmonary tuberculosis and diabetes is also good.
万方数据
维普
