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慢性阻塞性肺疾病患者发生社区获得性肺炎的影响因素

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目的:分析慢性阻塞性肺疾病(COPD)患者发生社区获得性肺炎的影响因素.方法:选取 2021 年 1 月至 2023 年 2 月该院收治的 186 例COPD患者进行横断面研究,收集患者的临床资料,检测患者血清炎性指标和血红蛋白(Hb)水平,采用BODE评分系统评估COPD患者生存状况,根据是否发生社区获得性肺炎将其分为发生组与未发生组,采用Logistic回归分析COPD患者发生社区获得性肺炎的影响因素.结果:186例COPD患者中,发生社区获得性肺炎63例,发生率为33.87%(63/186);两组性别、体质量指数、吸烟、合并低蛋白血症、合并高血压、BODE评分、近期应用抗生素、近期应用β2 受体激动剂、长期卧床、C反应蛋白(CRP)水平、Hb水平比较,差异均无统计学意义(P>0.05);发生组年龄≥70岁、合并糖尿病、机械通气、长期吸入糖皮质激素、家庭氧疗、降钙素原(PCT)≥2.0 ng/mL占比均高于未发生组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,年龄≥70 岁、合并糖尿病、机械通气、长期吸入糖皮质激素、家庭氧疗、PCT≥2.0 ng/mL均为COPD患者发生社区获得性肺炎的危险因素(OR>1,P<0.05).结论:年龄≥70 岁、合并糖尿病、机械通气、长期吸入糖皮质激素、家庭氧疗、PCT≥2.0 ng/mL均为COPD患者发生社区获得性肺炎的危险因素.
Influencing factors of community-acquired pneumonia in patients with chronic obstructive pulmonary disease
Objective:To analyze influencing factors of community-acquired pneumonia in patients with chronic obstructive pulmonary disease(COPD).Methods:A cross-sectional study was conducted on 186 patients with COPD admitted to this hospital from January 2021 to February 2023.The clinical data of these patients were collected.The inflammatory markers and hemoglobin(Hb)levels were detected.The BODE scoring system was used to evaluate the survival status of these COPD patients.According to whether community-acquired pneumonia occurred,they were divided into occurrence group and non-occurrence group.Logistic regression was used to analyze the influencing factors of community-acquired pneumonia in these COPD patients.Results:Among the 186 patients with COPD,63 cases of community-acquired pneumonia occurred,with an incidence of 33.87%(63/186).There were no significant differences in gender,body mass index,smoking,combined hypoproteinemia,combined hypertension,BODE score,recent application of antibiotics,recent application of β2 receptor agonists,long-term bed rest,C-reactive protein(CRP)level and Hb level between the two groups(P>0.05).The proportions of the patients with age≥70 years old,combined diabetes mellitus,mechanical ventilation,long-term inhalation of glucocorticoids,home oxygen therapy,and procalcitonin(PCT)≥2.0 ng/mL in the occurrence group were higher than those in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that age≥70 years,combined diabetes mellitus,mechanical ventilation,long-term inhalation of glucocorticoids,home oxygen therapy,and PCT≥2.0 ng/mL were all risk factors for community-acquired pneumonia in the COPD patients(OR>1,P<0.05).Conclusions:Age≥70 years,combined diabetes mellitus,mechanical ventilation,long-term inhalation of glucocorticoids,home oxygen therapy,and PCT≥2.0 ng/mL are the risk factors for community-acquired pneumonia in the COPD patients.

Chronic obstructive pulmonary diseaseCommunity-acquired pneumoniaInfluencing factor

高宇、李庆伟

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焦作煤业(集团)有限责任公司中央医院呼吸与危重症医学科,河南 焦作 454000

慢性阻塞性肺疾病 社区获得性肺炎 影响因素

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(3)
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