Application effects of Dexmedetomidine combined with Ropivacaine adductor canal block-assisted general anesthesia in total knee arthroplasty
Objective:To observe application effects of Dexmedetomidine combined with Ropivacaine adductor canal block-assisted general anesthesia in patients undergoing total knee arthroplasty(TKA).Methods:A prospective study was conducted on 110 patients with knee joint disease who underwent TKA in the hospital from March 2019 to March 2020.They were divided into observation group and control group according to the random number table method,55 cases in each.On the basis of general anesthesia,the control group was treated with Ropivacaine for ultrasound-guided adductor canal block,while the observation group was treated with Dexmedetomidine combined with Ropivacaine for adductor canal block.The nerve block effect[onset time of sensory block(OTSB),onset time of motor block(OTMB),duration of sensory block(DSB),duration of motor block(DMB)],the intraoperative hemodynamic indexes[mean arterial pressure(MAP)and heart rate after anesthesia induction(T0),at skin incision(T1),30 min after the surgery(T2)and at the end of operation(T3)]levels,the postoperative pain[visual analogue scale(VAS)]score,the anesthetic dosage,the postoperative analgesia pump pressing times,and the incidence of adverse reactions were compared between the two groups.Results:There were no significant differences in OTSB and OTMB between the two groups(P>0.05).The DSB and DMB in the observation group were longer than those in the control group,and the differences were statistically significant(P<0.05).At T1,T2 and T3,the levels of MAP and heart rate in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The VAS scores of the observation group 12,24 and 48 h after the surgery were lower than those of the control group,and the differences were statistically significant(P<0.05).The dosage of Propofol,Sufentanil,Remifentanil and the number of pressing times of postoperative analgesia pump in the observation group were less than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Dexmedetomidine combined with Ropivacaine adductor canal block-assisted general anesthesia for the TKA patients can shorten the onset time of anesthesia,prolong the duration of nerve block,maintain the intraoperative hemodynamic stability,improve the postoperative pain effects,and reduce the intraoperative and postoperative anesthetic dosages without increasing the incidence of adverse reactions.
万方数据
维普
