Effects of Fuyuan Tongluo decoction combined with conventional western medicine in treatment of patients with acute ischemic stroke of qi deficiency and blood stasis type
Objective:To observe effects of Fuyuan Tongluo decoction combined with conventional western medicine in treatment of patients with acute ischemic stroke(AIS)of qi deficiency and blood stasis type.Methods:A prospective study was conducted on 78 AIS patients admitted to this hospital from June 2021 to June 2023.They were divided into control group and observation group by using the random number table method,39 cases in each group.The control group was treated with conventional western medicine,while the observation group was treated with Fuyuan Tongluo decoction on the basis of that of the control group.The traditional Chinese medicine(TCM)syndrome score,the hemorheology index levels,the inflammatory index[interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP),monocyte chemoattractant protein-1(MCP-1)]levels,the neurological deficit degree[National Institutes of Health stroke scale(NIHSS)]score,and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:After the treatment,the scores of TCM syndromes such as partial numbness,hemiplegia,limb weakness,shortness of breath,fatigue,palpitations,spontaneous sweating,deviated tongue and dysphasia in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of whole blood high shear viscosity,erythrocyte aggregation index,plasma viscosity and whole blood low shear viscosity of the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The levels of IL-6,hs-CRP and MCP-1 in the two groups were lower than those before the treatment,those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The NHISS scores of the two groups were lower than those before the treatment,that in the observation group was lower than that in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Fuyuan Tongluo decoction combined with conventional western medicine can reduce the TCM syndrome scores,the hemorheology index levels,the inflammatory index levels and the NIHSS scores in the patients with AIS of qi deficiency and blood stasis type.Moreover,it is superior to single conventional western medicine treatment.
万方数据
维普
