Effects of Reduning injection combined withAmbroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution and Azithromycin injection in treatment of children with mycoplasma pneumonia
Objective:To observe effects of Reduning injection combined with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution and Azithromycin injection in treatment of children with mycoplasma pneumonia.Methods:A prospective study was conducted on 100 children with mycoplasma pneumonia admitted to this hospital from May 2022 to March 2023.According to the random number table method,they were divided into observation group and control group,50 cases in each group.The control group was treated with Azithromycin injection combined with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution,while the observation group was treated with Reduning injection on the basis of those of the control group.The total effective rate,the remission time of clinical symptoms,the levels of serum inflammatory factors[interleukin(IL)-6,tumor necrosis factor(TNF)-α,interferon-γ(IFN-γ)],and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 98.00%,which was significantly higher than 82.00%of the control group,and the difference was statistically significant(P<0.05).The remission time of clinical symptoms such as fever,cough,expectoration,lung rales and dyspnea in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of serum IL-6,TNF-α and IFN-γ in the two groups were lower than those before the treatment,and those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Reduning injection combined with Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution and Azithromycin injection in the treatment of the children with mycoplasma pneumonia can improve the total effective rate,shorten the remission time of clinical symptoms,and improve the levels of inflammatory factors.Moreover,it is superior to Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution combined with Azithromycin injection treatment.
Mycoplasma pneumoniaChildrenReduning injectionAmbroxol hydrochloride and Clenbuterol hydrochlorideAzithromycinInflammatory factorAdverse reaction
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