Effects of group B Streptococcus infection on maternal and infant outcomes in pregnant women in late pregnancy
Objective:To analyze effects of group B Streptococcus(GBS)infection on maternal and infant outcomes in pregnant women in late pregnancy.Methods:A prospective study was conducted on 4415 pregnant women in late pregnancy who underwent prenatal examination in the hospital from January to June 2023 GBS detection were performed.According to whether infected with GBS,they were divided into GBS positive group and GBS negative group.The GBS infection status of the pregnant women with different ages in late pregnancy and the drug sensitivity test results of the GBS positive pregnant women in late pregnancy were analyzed.The incidence of adverse maternal and infant outcomes was compared between the two groups.Results:Among the 4415 pregnant women in late pregnancy,244 were GBS positive,and the GBS infection rate was 5.53%(244/4415).The positive rate of GBS in the pregnant women with age of>35 years old was higher than that in the pregnant women with age of≤35 years old,and the difference was statistically significant(P<0.05).The sensitivity rates of the 244 GBS positive pregnant women in late pregnancy to Ampicillin,Vancomycin,Penicillin,and Ceftriaxone were 100.00%,and the resistance rates to Erythromycin,Clindamycin,Azithromycin,and Levofloxacin were 66.80%,62.30%,59.84%,and 56.97%,respectively.The resistance rates were high.The incidence of adverse maternal and infant outcomes such as premature rupture of membranes,premature delivery,postpartum hemorrhage,puerperal infection,fetal distress,neonatal pneumonia,and neonatal asphyxia in the GBS positive group were higher than those in the GBS negative group,and the difference was statistically significant(P<0.05).Conclusions:GBS infection in the pregnant women in late pregnancy can increase the incidence of adverse maternal and infant outcomes.
Pregnant women in late pregnancygroup B StreptococcusInfectionDrug sensitivity testMaternal and infant outcome
万方数据
维普
