Effects of neuroendoscopy-assisted bone flap hematoma removal in treatment of patients with hypertensive cerebral hemorrhage
Objective:To observe effects of neuroendoscopy-assisted bone flap hematoma removal in treatment of patients with hypertensive cerebral hemorrhage.Methods:A prospective study was conducted on 100 patients with hypertensive cerebral hemorrhage admitted to the hospital from June 2020 to June 2022.According to the random number table method,they were divided into control group and study group,50 cases in each group.The control group was treated with small bone window craniotomy,while the study group was treated with neuroendoscopy-assisted bone flap hematoma removal.The levels of operation-related indexes,and nerve injury indexes[neuron-specific enolase(NSE),glial fibrillary acidic protein(GFAP),central nervous system specific protein(S100β)]before and after the surgery,the neurological deficit degree[National Institutes of Health stroke scale(NIHSS)]score,the clinical efficacy,and the incidence of complications were compared between the two groups.Results:The operation time and the hospitalization time of the study group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,the hematoma clearance rate was higher than that of the control group,and the differences were statistically significant(P<0.05).1 week after the surgery,the levels of NSE,GFAP and S100β in the two groups were lower than those before the surgery,those in the study group were lower than those in t the control group,and the differences were statistically significant(P<0.05).1 month after the surgery,the NIHSS scores of the two groups were lower than those before the surgery,that in the study group was lower than that in the control group,and the differences were statistically significant(P<0.05).The total effective rate of treatment in the study group was 78.00% (39/50),which was higher than 54.00% (27/50)in the control group,and the difference was statistically significant(P<0.05).However,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Neuroendoscopy-assisted bone flap hematoma removal in the treatment of the patients with hypertensive cerebral hemorrhage can improve the total effective rate of treatment,improve the levels of operation-related indicators,and reduce the levels of nerve injury indexes and the scores of neurological deficit degree.Moreover,it is superior to small bone window craniotomy.
Hypertensive cerebral hemorrhageNeuroendoscopyBone flap hematoma removalSmall bone window craniotomyNerve injuryComplication
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