Effects of Montelukast sodium combined with Procaterol and Azithromycin in treatment of children with mycoplasma pneumonia complicated with acute attack of asthma
Objective:To observe effects of Montelukast sodium combined with Procaterol and Azithromycin in treatment of children with mycoplasma pneumonia complicated with acute attack of asthma.Methods:A prospective study was conducted on 150 children with mycoplasma pneumonia complicated with acute attack of asthma admitted to the hospital from February 2022 to June 2023.They were divided into study group and control group according to the random number table method,75 cases in each group.The control group was treated with Procaterol combined with Azithromycin,while the study group was treated with Montelukast sodium tablets on the basis of those of the control group.The total effective rate of treatment,the inflammatory factor[C-reactive protein(CRP),procalcitonin,white blood cell count(WBC)]levels,the asthma control test(ACT)score,the lung function indexes[forced expiratory volume in one second(FEV1),FEV1/forced vital capacity(FVC)]levels,the cough relieving time,the fever relieving time,the lung rale disappearance time,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 92.00% ,which was higher than 80.00% in the control group,and the difference was statistically significant(P<0.05).Three days after treatment,the ACT score,the FEV1 level and the FEV1/FVC level in the study group were higher than those in the control group,the levels of CRP,procalcitonin and WBC were lower than those in the control group,and the differences were statistically significant(P<0.05).The cough relieving time,the fever relieving time,the lung rale disappearance time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Montelukast sodium combined with Procaterol and Azithromycin in the treatment of the children with mycoplasma pneumonia complicated with acute attack of asthma can improve the total effective rate of treatment,the ACT scores and the lung function index levels,shorten the cough relieving time,the fever relieving time and the lung rale disappearance time,and reduce the levels of inflammatory factors.Moreover,it is superior to single Procaterol and Azithromycin treatment.
Montelukast sodiumProcaterolAzithromycinChildrenPneumoniaAsthmaLung function
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