Effects of Ginkgo biloba extract combined with Betahistine in treatment of patients with posterior circulation ischemic vertigo
Objective:To observe effects of Ginkgo biloba extract combined with Betahistine in treatment of patients with posterior circulation ischemic vertigo.Methods:A prospective study was conducted on 120 patients with posterior circulation ischemic vertigo admitted to this hospital from March 2020 to March 2023.According to the random number table method,they were divided into control group and study group,60 cases in each group.The control group was treated with Betahistine,while the study group was treated with Ginkgo biloba extract on the basis of that of the control group.Both groups were treated for 14 d.The clinical efficacy,the blood flow velocity of cerebral artery(left vertebral artery,right vertebral artery and basilar artery),the levels of inflammatory factors[high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the study group was 93.33% (56/60),which was higher than 80.00% (48/60)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the blood flow velocity of left vertebral artery,right vertebral artery and basilar artery in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of hs-CRP,IL-6 and TNF-α in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Ginkgo biloba extract combined with Betahistine in the treatment of the patients with posterior circulation ischemic vertigo can improve the total effective rate of treatment and the cerebral artery blood flow velocity,and reduce the levels of inflammatory factors.Moreover,it is superior to single Betahistine treatment.
万方数据
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