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康妇炎胶囊联合常规西药治疗慢性盆腔炎患者的效果

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目的:观察康妇炎胶囊联合常规西药治疗慢性盆腔炎(CPID)患者的效果.方法:回顾性分析 2021 年 4 月至 2023 年 4 月该院收治的94例CPID患者的临床资料,按照治疗方法不同将其分为对照组和观察组各47例.对照组采用常规西药(环丙沙星+甲硝唑)治疗,观察组在对照组基础上联合康妇炎胶囊治疗,两组均连续治疗 14 d.比较两组临床疗效,治疗前后中医证候积分、炎性因子[转化生长因子-β1(TGF-β1)、白细胞介素(IL)-6、IL-10]水平,以及不良反应发生率.结果:观察组治疗总有效率为 95.74%(45/47),高于对照组的 80.85%(38/47),差异有统计学意义(P<0.05);治疗后,观察组下腹胀痛、带下量多、色黄黏稠、腰骶酸痛等中医证候积分均低于对照组,差异有统计学意义(P<0.05);治疗后,观察组TGF-β1、IL-10 水平均高于对照组,IL-6 水平低于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:康妇炎胶囊联合常规西药治疗CPID患者可提高治疗总有效率,改善炎性因子水平,降低中医证候积分,效果优于单纯常规西药治疗.
Effects of Kangfuyan capsules combined with conventional western medicine in treatment of patients with chronic pelvic inflammatory disease
Objective:To observe effects of Kangfuyan capsules combined with conventional western medicine in treatment of patients with chronic pelvic inflammatory disease(CPID).Methods:The clinical data of 94 patients with CPID admitted to this hospital from April 2021 to April 2023 were retrospectively analyzed.According to different treatment methods,they were divided into control group and observation group,47 cases in each group.The control group was treated with conventional western medicine(Ciprofloxacin + Metronidazole),while the observation group was treated with Kangfuyan capsules on the basis of that of the control group.Both groups were treated for 14 d.The clinical efficacy,the Traditional Chinese Medicine(TCM)syndrome scores,the levels of inflammatory factors[transforming growth factor-β1(TGF-β1),interleukin(IL)-6,IL-10]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 95.74% (45/47),which was higher than 80.85% (38/47)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as lower abdominal distension and pain,more vaginal discharge,yellow and sticky vaginal discharge,and lumbosacral pain in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of TGF-β1 and IL-10 in the observation group were higher than those in the control group,the level of IL-6 was lower than that in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Kangfuyan capsules combined with conventional western medicine in the treatment of the CPID patients can improve the total effective rate of treatment,improve the levels of inflammatory factors,and reduce the scores of TCM syndromes.Moreover,it is superior to single conventional western medicine treatment.

Kangfuyan capsulesMetronidazoleCiprofloxacinChronic pelvic inflammatory diseaseTCM syndrome scoreInflammatory factorAdverse reaction

王宏明

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商丘市中心医院妇科,河南 商丘 476000

康妇炎胶囊 甲硝唑 环丙沙星 慢性盆腔炎 中医证候积分 炎性因子 不良反应

2024

中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
年,卷(期):2024.36(4)
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