Effects of Tianzhi granules combined with conventional Western medicine in treatment of patients with amnestic mild cognitive impairment
Objective:To observe effects of Tianzhi granules combined with conventional Western medicine in treatment of patients with amnestic mild cognitive impairment(aMCI).Methods:120 patients with aMCI admitted to this hospital from January 2020 to January 2021 were selected for the prospective study.According to the random number table method,they were divided into control group and study group,60 cases in each group.The control group was treated with conventional Western medicine,while the study group was treated with Tianzhi granules on the basis of that of the control group.The clinical efficacy,the cognitive function[mini-mental state examination(MMSE),Montreal cognitive assessment(MoCA)]scores,the memory ability[Rivermead behavioral memory test(RBMT)]score,and the incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of treatment in the study group was 91.67%(55/60),which was higher than 76.67%(46/60)in the control group,the difference was statistically significant(P<0.05).After the treatment,the scores of MMSE and MoCA in the two groups were higher than those before the treatment,those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The RBMT scores of the two groups were higher than those before the treatment,that in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Tianzhi granules combined with conventional Western medicine in the treatment of the patients with amnestic mild cognitive impairment can improve the total effective rate of treatment,the cognitive function scores and the memory ability scores.Moreover,it is superior to single conventional Western medicine treatment.