摘要
目的:分析子宫肌瘤术后患者发生下肢深静脉血栓(DVT)的影响因素.方法:选取 2022 年 1 月至 2023 年 5 月于该院行子宫肌瘤切除术的 114 例患者进行横断面研究.收集患者临床资料,检测凝血功能指标,术后随访 1 个月,观察患者下肢DVT发生情况,并根据是否发生下肢DVT将其分为发生组与未发生组,采用Logistic回归分析子宫肌瘤术后患者发生下肢DVT的影响因素.结果:114 例子宫肌瘤术后患者发生下肢DVT 28 例,发生率为 24.56%(28/114);两组体质量指数、户籍所在地、职业类型、饮酒史、吸烟史、合并高血压情况、肌瘤类型、肌瘤数量、肌瘤直径、手术时间、术中出血量、凝血酶时间(TT)、纤维蛋白原(FIB)水平比较,差异均无统计学意义(P>0.05);发生组年龄≥35 岁、合并糖尿病、术后卧床时间≥6 h、凝血酶原时间(PT)<13 s、活化部分凝血活酶时间(APTT)<23 s占比均高于未发生组,术后抗凝治疗或穿戴弹力袜占比低于未发生组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,年龄≥35岁、合并糖尿病、术后卧床时间≥6 h、PT<13 s、APTT<23 s均为子宫肌瘤术后患者发生下肢DVT的危险因素(OR>1,P<0.05),术后抗凝治疗或穿戴弹力袜为子宫肌瘤术后患者发生下肢DVT的保护因素(OR<1,P<0.05).结论:年龄≥35 岁、合并糖尿病、术后卧床时间≥6 h、PT<13 s、APTT<23 s均为子宫肌瘤术后患者发生下肢DVT的危险因素,术后抗凝治疗或穿戴弹力袜为子宫肌瘤术后患者发生下肢DVT的保护因素.
Abstract
Objective:To analyze influencing factors of deep venous thrombosis(DVT)of lower extremity in patients after uterine fibroids surgery.Methods:A cross-sectional study was conducted on 114 patients who underwent uterine fibroids surgery in the hospital from January 2022 to May 2023.The clinical data of these patients were collected.The coagulation function index levels were detected.These patients were followed up for 1 month.The incidence of lower extremity DVT was evaluated.According to whether lower extremity DVT occurred,they were divided into occurrence group and non-occurrence group.Logistic regression was used to analyze the influencing factors of lower extremity DVT in the patients after uterine fibroids surgery.Results:28 cases of lower extremity DVT occurred in the 114 patients after uterine fibroids surgery,with an incidence of 24.56%(28/114).There were no significant differences in body mass index,household registration location,occupational type,drinking,smoking,combined hypertension,type of fibroids,number of fibroids,diameter of fibroids,operation time,intraoperative blood loss,thrombin time(TT)and fibrinogen(FIB)level between the two groups(P>0.05).The proportions of the patients with age≥35 years old,combined diabetes mellitus,postoperative bed time≥6 h,prothrombin time(PT)<13 s,activated partial thromboplastin time(APTT)<23 s in the occurrence group were higher than those in the non-occurrence group,the proportions of the patients with postoperative anticoagulant therapy or wearing elastic stockings was lower than that in the non-occurrence group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that age≥35 years,combined diabetes mellitus,postoperative bed time≥6 h,PT<13 s,APTT<23 s were risk factors for lower extremity DVT in the patients after uterine fibroids surgery(OR>1,P<0.05),while postoperative anticoagulant therapy or wearing elastic stockings were protective factors(OR<1,P<0.05).Conclusions:Age≥35 years old,combined diabetes mellitus,postoperative bed time≥6 h,PT<13 s,APTT<23 s are the risk factors for lower extremity DVT in the patients after uterine fibroids surgery,while postoperative anticoagulant therapy or wearing elastic socks are the protective factors.
维普
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